Lorimer Moseley: Pain, Stimulus and Meaning

What does it mean when pain changes while the stimulus remains the same? Lorimer Moseley looks at the complexity of pain beyond nociception.

The re­searchers thought, “Ahhh, pain equals C-fibers plus A-delta fibers.”

Can you see how intuitively sensible and at­tractive that is? Now, for those of you who have written that down as fact, you should get ready to cross it out.

If that is fact, we should look for a few con­sistent themes when we look at the relationship between pain and nociception (the sensory nervous system’s response to certain harmful or potentially harmful stimuli).

For example, if nociception is the substrate for pain, if we should see no change in pain with­out a change in nociception, then we should see no change in nociception without a change in pain.

You can actually test this quite easily. You can do an experiment where you deliver a con­sistent nociceptive stimulant, which is what we did some time ago.

We had a very cold piece of metal and we put it on people’s hands. We simultaneously showed them a light. We didn’t tell them anything about the light. We just made it very clear the light was coinciding in time and was related to this very cold stimulus.

The light was either red or blue. This is what happened when they saw a red light. This is their pain rating. This is what happened when they saw a blue light. Each of these yellow lines is an indi­vidual.

Some of them are not affected in any way. The light color does not affect how much pain they experience. However, some of them have no pain with the blue light and eight out of 10 with the red light.

The stimulus is identical, so there’s a very large variability between individuals, but clearly the systematic effect is the color of this light is changing pain, but not changing nociception. If we put it onto this fig­ure, we would show: C-fibers haven’t changed what they’re doing and A-delta fibers haven’t changed what they’re doing. However, the pain is greater when it’s red and the pain is less when it’s blue.

This is the theme that’s been coming across for 20 years in experimental and clinical data. The critical thing is meaning. It’s all about what it means, and we can capture that as clinicians.

There are a lot of things we can capture. In fact, Americans are better at capturing some aspects that are very important, for example, how you present yourself as a health professional. Americans often wear ties and stethoscopes.

I know a physio friend of mine who wears a stethoscope. He never uses it. He might as well stitch it into his collar. He probably has actually, but he’s convinced it gets him better results. That makes sense to me. It’s all about meaning.


Lorimer Moseley Pain Research Video

$39.00$49.00

Top clinical researcher Professor Lorimer Moseley explains why things hurt, why they keep hurting and how to help prevent and manage pain. You’ll learn strategies and frameworks to build better treatments to help get your patients back to normal and free of pain. This is also a valuable education for non-clinical coaches and trainers as well.

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